Makenna is the descendant of a Maltese family with a unique link to vampirism. In every century or two, a few members in her family line would be chosen by her ancestor, Luca, to become vampires to protect and provide for the family: Makenna was one of the chosen ones. She looked forward to her destiny until she met Charles in Barcelona in the 1940s.
Charles was born in the early 20th century of Denmark. In his early twenties, he moved to Barcelona to study law. There, he met and fell in love with a Maltese woman named Makenna.
Makenna and Charles met when he was a law student in Barcelona and fell in love. Makenna's ancestor, Luca, told her that she could abandon her destiny of becoming a vampire if she wanted a normal life with Charles. However, she still chose immortality. Before she left, she promised Charles that she will return. Makenna waited for her newborn year to pass while Charles waited for her return.
After she left her newborn state behind, she found Charles again, who was still waiting for her. After telling him about life as a vampire, Charles decided to join her. They waited 3 years for Makenna to practice her self-control to avoid killing him by accident.
After he was successfully changed and found out about his power of lie detection, they lived a nomadic lifestyle together, but Makenna still visited her family often.
- "We did not come here for a fight. We came here to witness. And our witness is that this condemned family is innocent."
- ―Makenna's witness.[src]
In late 2006, Makenna and Charles are both invited by Renata, Makenna's distant relative, to join the Volturi's cause of bringing 'justice' to the Cullen family for allegedly creating an immortal child. Because the Volturi truly believe Renesmee is an immortal child at the time, Charles senses no dishonesty and agrees to join them and Makenna complies as well.
They then follow the coven to Forks where a confrontation takes place; everyone learns that the supposed immortal child is in fact a vampire-human hybrid, and that the whole situation has been a misunderstanding.
The two mostly remain in the background as the confrontation progresses. When Garrett tells the Volturi's witnesses to pick their own sides as the Volturi will surely kill them all to keep the truth from being spread, Charles finally senses the deceitful words coming from Aro. He 'confirms' that the Cullens are innocent, and takes his leave with Makenna. Other vampries begin to take their leave as well.